نتایج جستجو برای: Liver genes
تعداد نتایج: 735201 فیلتر نتایج به سال:
objective(s): stem cell therapy is believed to be as a promising treatment strategy for tissue repair and regeneration. the plasticity specification of the adult stem cells, such as mscs, has enabled that these cells to be used in the treatment of a broad spectrum of diseases like liver disorders. in this study, the production of urea and albumin (alb), glycogen storage, and expression of some ...
Background and Aim: Non-Alcoholic Fatty Liver Disease (NAFLD) is the major cause of chronic liver disease in developed countries. In this study, we identified the most important transcription factors and biological mechanisms affecting the incidence of fatty liver disease using the promoter region data mining. Materials and Methods In this study, at first, the marker genes associated with this...
Effects of fibromodulin protein expression on NFkB and TGFβ signaling pathways in liver cancer cells
Introduction: The incidence rate of liver cancer is continuously increasing. Currently, gene therapy is applied to improve various medical issues such as cancer treatment approaches. Correspondingly, fibromodulin involves in many biological and physiological processes through interaction with growth factors and signaling pathway receptors. The aim of this study was to investigate the effects of...
Morphine and kisspeptin influences on 5-α reductase and aromatase gene expression in adult male rats
Objective(s): Kisspeptin and opioids are important factors for controlling GnRH/LH secretion. In present study, influences of kisspeptin or morphine were investigated on 5α- reductase or aromatase (CYP19) genes expression in the hypothalamus, testis and liver. It aimed to investigate whether kisspeptin pathway may control morphine effects on plasma concentration of tes...
prior investigators demonstrated helicobacter pylori as a risk factor of liver diseases. in this study association between h. pylori and hepatocellular carcinoma was investigated. patients and methods totally, 59 specimens of liver were collected from two health care centers affiliated to shahid beheshti university of medical sciences, including 22 specimens of hepatocellular carcinoma, 18 spec...
Objective(s): As a multifunctional molecule, NO has different effects on liver injury. The present work aimed to investigate the effects of Nos2 knockout (KO) on acute liver injury in aged mice treated with carbon tetrachloride (CCl4). Materials and Methods: The acute liver injury model was produced by CCl4 at 10 ml/kg body weight in 24-...
Growth hormone-activated STAT5b is an essential regulator of sex-differential gene expression in mouse liver; however, its impact on hepatic and epigenetic responses poorly understood. Here, we found a substantial, albeit incomplete loss liver sex bias hepatocyte-specific STAT5a/STAT5b (collectively, STAT5)-deficient liver. In male liver, many male-biased genes were downregulated direct associa...
Background: The use of testosterone enanthate has increased among athletes, especially in resistance disciplines. Considering the side effects of using testosterone enanthate, it seems necessary to find alternative methods. The present study compared the independent and interactive effects of resistance training, testosterone and palm pollen extract on mRNA expression of MFN2, FISS and DRP1 gen...
background alcoholic hepatitis (ah) is an acute manifestation of alcoholic liver disease with high mortality rates. objectives our aim was to study the molecular mechanisms of ah. materials and methods the differentially expressed genes (degs) in liver between ah and control cases were identified by analyzing the gse28619 microarray data using t-test. the kyoto encyclopedia of genes and genomes...
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